Some comprehensive information of ivermectin in COVID-19 can be found below.
- The Totality of Evidence (ivermectin): https://covid19criticalcare.com/wp-content/uploads/2021/08/SUMMARY-OF-THE-EVIDENCE-BASE-FINAL.pdf
- Review of Emerging Evidence: https://covid19criticalcare.com/wp-content/uploads/2021/08/SUMMARY-OF-THE-EVIDENCE-BASE-FINAL.pdf
- A compilation of all current controlled trials results for Ivermectin in COVID-19 can be found here: ivmmeta.com
- Ivermectin is a generally safe medication and has been used over 4 billion times in people around the world for over 30 years in the treatment of parasitic diseases and at those doses and durations, its side effects are considered by the WHO to be generally “minor and transient.” The safety of ivermectin at the doses and durations used in COVID-19 can be reviewed here: Safety of Ivermectin: https://covid19criticalcare.com/wp-content/uploads/2021/09/FLCCC-Information-Evidence-for-Safety-of-Ivermectin.pdfreview
IVM Interactions and safe usage notes:
These are the common side effects reported with ivermectin in general:
Cardiovascular: Tachycardia (4%), peripheral edema (3%), facial edema (1%), orthostatic hypotension (1%)
Central nervous system: Dizziness (3%)
Gastrointestinal: Diarrhea (2%), nausea (2%)
At higher doses used for long covid a small percentage of patients complain of visual changes that quickly resolve when the dose is reduced or the medication is stopped. Eye exams in these patients have not shown any abnormalities, but inflammation of various parts of the eye is possible with ivermectin.
Although considered safe in pregnancy, that conclusion was derived from decades of use at parasite dose and durations. In COVID, there is no safety data, thus we generally avoid in most circumstances with pregnant patients as there are safer alternatives.