Home » Off-Label Medicines » Hydroxychloroquine

Hydroxychloroquine is considered generally safe and likely effective for prevention and early treatment, but may not be effective later in the course of illness. effects. Most adverse effects are rare or only associated with higher doses over years of use.

Some common adverse effects include stomach upset. dizziness, and shortness of breath or muscle weakness and tenderness. Most other described side effects are almost all associated only with longer term use/dosing, i.e. retinopathy, myopathy, neuropsychiatric disorders, cardiomyopathy, and QT syndrome.

Dosage adjustment for concomitant therapy: Significant drug interactions exist, requiring dose/frequency adjustment or avoidance. Consult drug interactions database for more information.

Administration: Adult

Oral: Administer with food or milk. Do not crush or divide film-coated tablets per the manufacturer; the tablets have a bitter taste (McLaughlin 1991). In patients unable to swallow tablets, it has been recommended that tablets may be crushed and mixed with a small amount of applesauce, chocolate syrup, or jelly (CDC Yellow Book 2020), or an extemporaneous suspension may be compounded (See Extemporaneously Prepared).

Based on data compiled by various physicians around the world we believe HCQ is effective at preventing and treating COVID-19 in early stages and can be safely used off-label in humans for this indication. One of the most convincing sources of proof of its efficacy is the largest natural observational drug trial ever conducted totaling about 2.5 billion people:
https://hcqtrial.com/ The most comprehensive meta analysis of worldwide studies confirms the results: hcqmeta.com

Drug Interactions of hydroxychloroquine can be checked here: https://www.webmd.com/interaction-checker/default.htm.